LiftoffTools: a toolkit for comparing gene annotations mapped between genome assemblies

In 2020 we published Liftoff, which was the first standalone tool specifically designed for transferring gene annotations between genome assemblies of same or closely related species. While content is expected to be very similar in genomes, differences may biologically consequential, and a computational method extract all gene-related should prove useful analysis such genomes. Here present LiftoffTools, toolkit automate detection sequence variants, synteny, copy number changes.  We provide description an example its use comparing genes mapped two human assemblies.